1. Anti-infection
  2. HIV
  3. 18A

18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env.

For research use only. We do not sell to patients.

18A Chemical Structure

18A Chemical Structure

CAS No. : 331261-50-8

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Description

18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env[1].

IC50 & Target

HIV-1[1].

In Vitro

18A (0.01-10 µM; 40-44 h) shows specific inhibition of HIV-1JR-FL infection of human PBMCs (IC50 = 0.4 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: PBMCs
Concentration: 0.01-10 µM
Incubation Time: 40-44 h
Result: Inhibited infection of HIV-1JR-FL, with an IC50 value of 0.4 μM.
Molecular Weight

313.33

Formula

C14H11N5O2S

CAS No.
SMILES

OC(C=C1)=CC=C1/C=N/NC(NC2=CC=CC3=NSN=C23)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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18A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
18A
Cat. No.:
HY-110253
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