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Ceftazidime pentahydrate

(Synonyms: GR20263 pentahydrate)
46 Cited Publications
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Based on 46 publication(s) in Google Scholar

Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.

For research use only. We do not sell to patients.

  • Purity: 99.94%
  • CAS No.: 78439-06-2
  • Formula: C22H32N6O12S2
  • Molecular Weight:636.65
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Ceftazidime pentahydrate Chemical Structure
    Ceftazidime pentahydrate Chemical Structure
  • Experimental Validation Results for Ceftazidime pentahydrate
  • Experimental Validation Results for Ceftazidime pentahydrate
  • Experimental Validation Results for Ceftazidime pentahydrate
  • Experimental Validation Results for Ceftazidime pentahydrate
  • Experimental Validation Results for Ceftazidime pentahydrate
CAS No.: 78439-06-2
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  • Ceftazidime pentahydrate Chemical Structure
    Ceftazidime pentahydrate Chemical Structure
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    Ceftazidime pentahydrate purchased from MedChemExpress. Usage Cited in: Mol Syst Biol. 2025 Jun 30. [Abstract]

    Customer Validation
     Growth and cadaverine production dynamics in E. coli treated with 20 µM of Ceftazidime. Treated cultures show a brief period where the optical density (Absorbance, 595 nm) increases, concurrent with a burst of cadaverine production far above untreated levels. This indicates that this β-lactam antibiotic does not immediately kill the cells but allows for a brief period of growth and stress-induced polyamine production prior to bacterial cell lysis. Lines indicate the mean, and shaded areas the standard deviation of n = 6 biological replicates.

  • 1/16

    Ceftazidime pentahydrate purchased from MedChemExpress. Usage Cited in: AMB Express. 2024 Dec 24;14(1):141. [Abstract]

    Customer Validation
     Combinational antimicrobial effects between PVB and conventional antibiotics against MRSA ATCC 43,300. TET, Tetracycline. DOX, Doxycycline. E, Erythromycin. AZI, Azithromycin. P, Penicillin. CAZ, Ceftazidime. AMP, Ampicillin. CEZ, Cefazolin. CEF, Cefotaxime. OXA, Oxacillin. CRO, Ceftriaxone. AMK, Amikacin. GEN, Gentamycin, KANA, Kanamycin. TOB, Tobramycin. SPC, Spectinomycin.

  • 1/16

    Ceftazidime pentahydrate purchased from MedChemExpress. Usage Cited in: Microorganisms. 2024 Mar 13;12(3):575. [Abstract]

    Customer Validation
     Percentages of E. coli strains showing antimicrobial resistance to different antimicrobial agents. AMP, Ampicillin; CAZ, Ceftazidime; IPM, Imipenem; MRP, Meropenem; GEN, Gentamicin; OFX, Ofloxacin; SXT, Trimethoprim–sulfamethoxazole; TET, Tetracycline; TGC, Tigecycline; CL, Colistin; FFC, Florfenicol.

  • 1/16

    Ceftazidime pentahydrate purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2022 Sep 30;77(10):2803-2808. [Abstract]

    Customer Validation
     In vivo change in log10 cfu/thigh of each isolate treated with saline control, Ceftazidime 2 g IV q8h 2 h infusion HSR, Ceftazidime/Avibactam 2.5 g q8h 2 h infusion HSR or meropenem 2 g q8h 3 h infusion HSR for three P. aeruginosa with inserted GES β-lactamases. (a) PSA 2136, with inserted GES-1 (ESBL). (b) PSA 2137, with inserted GES-5 (carbapenemase). (c) PSA 2138, with inserted GES-15. P values in the boxes represent the results from one-way ANOVA; P values are presented if between-group differences were present. The x-axis describes the treatment HSR [MIC (mg/L), % fT>MIC]. CAZ, Ceftazidime; CAZ-AVI, Ceftazidime/Avibactam; MEM, meropenem.

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    Ceftazidime pentahydrate purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858. [Abstract]

    Customer Validation
     The cumulative MIC distributions of Cefepime/Taniborbactam, Ceftazidime/Avibactam and comparator Meropenem for 500 tested isolates. The MICs of cefepime and Cefepime/Taniborbactam shown in the figure were tested by the broth microdilution method. The MICs of Meropenem shown in the figure were tested by the agar dilution method. SS, susceptible to all tested β-lactams. SS-P. aeruginosa, meropenem-susceptible P. aeruginosa. Nine IMP producers included three blaIMP-producing P. aeruginosa.

  • Ceftazidime pentahydrate