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Polymyxin B Sulfate

26 Cited Publications
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Based on 26 publication(s) in Google Scholar

Polymyxin B Sulfate is an antibiotic. Polymyxin B Sulfate inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B Sulfate neutralizes the effect of endotoxin. Polymyxin B Sulfate induces bacterial death by increasing its permeability. Polymyxin B Sulfate is used in endotoxemia research.

For research use only. We do not sell to patients.

  • Purity: 96.88%
  • CAS No.: 1405-20-5
  • Molecular Weight:1199.75 (average)
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Polymyxin B Sulfate Chemical Structure
    Polymyxin B Sulfate Chemical Structure
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
  • Experimental Validation Results for Polymyxin B Sulfate
CAS No.: 1405-20-5
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Cell Proliferation/Viability AssayGel ElectrophoresisMicrobiological AssayBio/Physico-chemical AssayCell Imaging/StainingHistological Imaging/StainingIn Vivo Efficacy Study
  • Gel Electrophoresis
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  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Proliferation/Viability Assay
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  • Microbiological Assay
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  • Polymyxin B Sulfate Chemical Structure
    Polymyxin B Sulfate Chemical Structure
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  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

    Customer Validation
     Electrophoretic migration of Td and the Polymyxin B@Td nanocomplex at different gradient mixture ratios (Polymyxin B: Td = 10:1, 50:1, and 100:1).

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

    Customer Validation
     Analysis of the zeta potentials of Polymyxin B, Td, and the Polymyxin B@Td nanocomplex.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

    Customer Validation
     Penetration of free or Td-bound Polymyxin B into a bacterial biofilm, as characterized by CLSM (blue: Hoechst33342-stained bacteria; green: FITC-labeled Td; red: Cy5-labeled Polymyxin B). Scale bar: 50 μm.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

    Customer Validation
     SEM analysis of biofilm structural disruption by Polymyxin B and Polymyxin B@Td. Red arrows: biofilm matrix components. Red dotted-line square: representative dead bacteria. Scale bar: 5–3 μm.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: J Control Release. 2025 May 30:113907. [Abstract]

    Customer Validation
     Antimicrobial effects of PMB-LNPs. MIC and Polymyxin B values of Polymyxin B -LNPs or free Polymyxin B against E. coli, A. baumannii.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     The cytotoxicity assessment of PEG-pHSA@PMB nanoparticles. The toxicity of Polymyxin B Sulfate (PMB, 24 h), PEG-pHSA@PMB, and PEG-pHSA to HBE cells was detected by the CCK-8 kit.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     Polymyxin B Sulfate, 4 μg/mL. The bacteriostasis curves of the drugs. The OD600 value of the CRKP suspension was determined at different times.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     The load of CRKP in the lungs of mice that inhaled different drugs. The bacterial load of CRKP in the lungs of pneumonia mice treated with inhaled drugs (equivalent to 4 mg/kg loaded Polymyxin B Sulfate) was measured by the bacterial plate counting method.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     PEG-pHSA@PMB (4 mg/kg loaded Polymyxin B Sulfate). HE staining of lung sections of CRKP pneumonia mice treated with different drugs. The scale bar is 50 μm.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     PEG-pHSA@PMB (4 mg/kg loaded Polymyxin B Sulfate). The statistical chart of lung injury score by HE staining of lung tissue in each group, n = 9.

  • 1/16

    Polymyxin B Sulfate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Feb 18:31:101590. [Abstract]

    Customer Validation
     HE staining of different tissues in mice treated with different drugs. The HE staining results of the lungs, kidneys, brains, hearts, livers, and spleens of ICR mice were examined after inhaling 30 μL of different drugs (equivalent to 8 mg/kg loaded Polymyxin B Sulfate) three times daily for 3 days, n = 5. The scale bar is 100 μm.

  • Polymyxin B Sulfate