DBCO-PEG13-DBCO
Based on 1 Customer Validation
DBCO-PEG13-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG13-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 95.24%
- Formula: C66H86N4O17
- Molecular Weight:1207.41
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Oil
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Molecular Weight 1207.41
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Formula C66H86N4O17
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Color Colorless to light yellow
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SMILES
O=C(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (82.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.8282 mL | 4.1411 mL | 8.2822 mL | 20.7055 mL |
| 5 mM | 0.1656 mL | 0.8282 mL | 1.6564 mL | 4.1411 mL | |
| 10 mM | 0.0828 mL | 0.4141 mL | 0.8282 mL | 2.0705 mL | |
| 15 mM | 0.0552 mL | 0.2761 mL | 0.5521 mL | 1.3804 mL | |
| 20 mM | 0.0414 mL | 0.2071 mL | 0.4141 mL | 1.0353 mL | |
| 25 mM | 0.0331 mL | 0.1656 mL | 0.3313 mL | 0.8282 mL | |
| 30 mM | 0.0276 mL | 0.1380 mL | 0.2761 mL | 0.6902 mL | |
| 40 mM | 0.0207 mL | 0.1035 mL | 0.2071 mL | 0.5176 mL | |
| 50 mM | 0.0166 mL | 0.0828 mL | 0.1656 mL | 0.4141 mL | |
| 60 mM | 0.0138 mL | 0.0690 mL | 0.1380 mL | 0.3451 mL | |
| 80 mM | 0.0104 mL | 0.0518 mL | 0.1035 mL | 0.2588 mL |
DBCO-PEG13-DBCO Related Classifications
HY-140305 Related Classifications
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