(S,R,S)-AHPC-Me-C6-NH2
Based on 1 Customer Validation
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 2411422-49-4
- Formula: C30H45N5O4S
- Molecular Weight:571.77
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
In Vitro
(S,R,S)-AHPC-Me-C6-NH2 is used to couple with oseltamivir moieties via amide condensation to construct Oseltamivir (HY-13317)-PROTACs, which induce the degradation of viral neuraminidase (NA), inhibit influenza virus replication in MDCK cells, and show potent inhibitory activity against both wild-type and Oseltamivir-resistant influenza strains in vitro[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2411422-49-4
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Appearance Solid
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Molecular Weight 571.77
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Formula C30H45N5O4S
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Color Off-white to light yellow
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SMILES
NCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (174.90 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7490 mL | 8.7448 mL | 17.4895 mL | 43.7239 mL |
| 5 mM | 0.3498 mL | 1.7490 mL | 3.4979 mL | 8.7448 mL | |
| 10 mM | 0.1749 mL | 0.8745 mL | 1.7490 mL | 4.3724 mL | |
| 15 mM | 0.1166 mL | 0.5830 mL | 1.1660 mL | 2.9149 mL | |
| 20 mM | 0.0874 mL | 0.4372 mL | 0.8745 mL | 2.1862 mL | |
| 25 mM | 0.0700 mL | 0.3498 mL | 0.6996 mL | 1.7490 mL | |
| 30 mM | 0.0583 mL | 0.2915 mL | 0.5830 mL | 1.4575 mL | |
| 40 mM | 0.0437 mL | 0.2186 mL | 0.4372 mL | 1.0931 mL | |
| 50 mM | 0.0350 mL | 0.1749 mL | 0.3498 mL | 0.8745 mL | |
| 60 mM | 0.0291 mL | 0.1457 mL | 0.2915 mL | 0.7287 mL | |
| 80 mM | 0.0219 mL | 0.1093 mL | 0.2186 mL | 0.5465 mL | |
| 100 mM | 0.0175 mL | 0.0874 mL | 0.1749 mL | 0.4372 mL |