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  3. Fenaminosulf

Fenaminosulf is a plant immune modulator and mutagen. Fenaminosulf impairs plant immune recognition and signal transduction by inhibiting the activities of key kinases such as Xa21 and PBL19, thereby regulating the expression of genes related to hormone metabolism, phenylpropane biosynthesis, and plant-pathogen interactions. Fenaminosulf affects the growth and gall formation of Zizania latifolia in a concentration-dependent manner. Fenaminosulf induces mutations in bacterial systems and causes plant chromosome aberrations, but shows no mutagenic activity or lethal effect in Drosophila melanogaster. Fenaminosulf exhibits inconsistent carcinogenicity in rat studies.

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Fenaminosulf

Fenaminosulf Chemical Structure

CAS No. : 140-56-7

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Description

Fenaminosulf is a plant immune modulator and mutagen. Fenaminosulf impairs plant immune recognition and signal transduction by inhibiting the activities of key kinases such as Xa21 and PBL19, thereby regulating the expression of genes related to hormone metabolism, phenylpropane biosynthesis, and plant-pathogen interactions. Fenaminosulf affects the growth and gall formation of Zizania latifolia in a concentration-dependent manner. Fenaminosulf induces mutations in bacterial systems and causes plant chromosome aberrations, but shows no mutagenic activity or lethal effect in Drosophila melanogaster. Fenaminosulf exhibits inconsistent carcinogenicity in rat studies[1][2].

In Vitro

Fenaminosulf induces mutagenic activity in Salmonella typhimurium[2].
Fenaminosulf induces mutagenic activity and interacts with DNA in Bacillus subtilis[2].
Fenaminosulf induces chromosome aberrations in higher plant cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Fenaminosulf (1.25-5 g/L; foliar; three applications at seven-day intervals) exerts concentration-dependent effects on Zizania latifolia, with 1.25 g/L promoting vegetative growth, 5 g/L and 2.5 g/L increasing gall formation rates to up to ~85% and ~75% respectively at 100 days[1].
Fenaminosulf (10 mg/100 mL food medium; p.o.; continuous exposure via feeding during mating and larval development) does not induce sex-linked recessive lethal mutations in Drosophila melanogaster[2].
Fenaminosulf (250 mg/kg feed; p.o.; daily; 17 months) does not induce tumor formation in Sprague-Dawley rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Meirenjiao Zizania latifolia[1]
Dosage: 1.25 g/L; 2.5 g/L; 5 g/L
Administration: foliar; three applications at seven-day intervals
Result: Significantly increased plant height and leaf length compared to control at 7, 14, and 21 days post-treatment at 1.25 g/L.
Maintained chlorophyll content similar to control at 1.25 g/L.
Molecular Weight

251.24

Formula

C8H10N3NaO3S

CAS No.
SMILES

O=S(/N=N/C1=CC=C(N(C)C)C=C1)(O[Na])=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Fenaminosulf
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HY-127158
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