Cyclomarin monomer-2
Based on 1 Customer Validation
Cyclomarin monomer-2 (Compound 10), a cyclomarin monomer, is a pre-dimerization precursor that can form Homo-BacPROTACs targeting the degradation of ClpC1. Cyclomarin monomer-2 binds to the Mtb ClpC1 protein with a KD of 4.0 nM. The MIC of Cyclomarin monomer-2 against the Mtb H37Rv standard strain is 3.1 μM. Cyclomarin monomer-2 can be used as a key intermediate in the development of Homo-BacPROTACs.
For research use only. We do not sell to patients.
- Purity: 97.40%
- Formula: C49H68N8O9
- Molecular Weight:913.11
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 913.11
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Formula C49H68N8O9
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (109.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0952 mL | 5.4758 mL | 10.9516 mL | 27.3790 mL |
| 5 mM | 0.2190 mL | 1.0952 mL | 2.1903 mL | 5.4758 mL | |
| 10 mM | 0.1095 mL | 0.5476 mL | 1.0952 mL | 2.7379 mL | |
| 15 mM | 0.0730 mL | 0.3651 mL | 0.7301 mL | 1.8253 mL | |
| 20 mM | 0.0548 mL | 0.2738 mL | 0.5476 mL | 1.3689 mL | |
| 25 mM | 0.0438 mL | 0.2190 mL | 0.4381 mL | 1.0952 mL | |
| 30 mM | 0.0365 mL | 0.1825 mL | 0.3651 mL | 0.9126 mL | |
| 40 mM | 0.0274 mL | 0.1369 mL | 0.2738 mL | 0.6845 mL | |
| 50 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5476 mL | |
| 60 mM | 0.0183 mL | 0.0913 mL | 0.1825 mL | 0.4563 mL | |
| 80 mM | 0.0137 mL | 0.0684 mL | 0.1369 mL | 0.3422 mL | |
| 100 mM | 0.0110 mL | 0.0548 mL | 0.1095 mL | 0.2738 mL |
Cyclomarin monomer-2 Related Classifications
HY-P11498 Related Classifications
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