4'-C-Azidouridine (Synonyms: 4'-Azidouridine)

Cat. No.: HY-77650: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

4'-C-Azidouridine Chemical Structure

CAS No. : 139442-01-6

Size	Price	Stock
50 mg	USD 850	Ask For Quote & Lead Time
100 mg	USD 1380	Ask For Quote & Lead Time

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Description

4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents^[1]. 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Molecular Weight

285.21

Formula

C₉H₁₁N₅O₆

CAS No.

139442-01-6

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@](CO)(N=[N+]=[N-])O[C@H]1N2C(NC(C=C2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (350.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5062 mL	17.5309 mL	35.0619 mL
5 mM	0.7012 mL	3.5062 mL	7.0124 mL
10 mM	0.3506 mL	1.7531 mL	3.5062 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (276 KB) SDS (0 KB)

COA (256 KB) HNMR (250 KB)

Handling Instructions (2659 KB)

References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5062 mL	17.5309 mL	35.0619 mL	87.6547 mL
	5 mM	0.7012 mL	3.5062 mL	7.0124 mL	17.5309 mL
	10 mM	0.3506 mL	1.7531 mL	3.5062 mL	8.7655 mL
	15 mM	0.2337 mL	1.1687 mL	2.3375 mL	5.8436 mL
	20 mM	0.1753 mL	0.8765 mL	1.7531 mL	4.3827 mL
	25 mM	0.1402 mL	0.7012 mL	1.4025 mL	3.5062 mL
	30 mM	0.1169 mL	0.5844 mL	1.1687 mL	2.9218 mL
	40 mM	0.0877 mL	0.4383 mL	0.8765 mL	2.1914 mL
	50 mM	0.0701 mL	0.3506 mL	0.7012 mL	1.7531 mL
	60 mM	0.0584 mL	0.2922 mL	0.5844 mL	1.4609 mL
	80 mM	0.0438 mL	0.2191 mL	0.4383 mL	1.0957 mL
	100 mM	0.0351 mL	0.1753 mL	0.3506 mL	0.8765 mL

4'-C-Azidouridine Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-C-Azidouridine139442-01-64'-AzidouridineNucleoside Antimetabolite/AnaloganticonvulsantanxiolyticantiepilepticantihypertensiveInhibitorinhibitorinhibit

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