4'-C-Azidouridine
4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 139442-01-6
- 分子式: C9H11N5O6
- 分子量:285.21
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
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| T-cell | IC50 |
73 μM
Compound: 6b
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Compound was tested in vitro for inhibition of cytopathogenicity of LAV(IIIB) in CD4+ T-cells (A3.01)
Compound was tested in vitro for inhibition of cytopathogenicity of LAV(IIIB) in CD4+ T-cells (A3.01)
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[PMID: 1573638] |
化学情報
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CAS 番号 139442-01-6
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性状 Solid
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分子量 285.21
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分子式 C9H11N5O6
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Color White to off-white
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SMILES
O[C@@H]1[C@H](O)[C@](CO)(N=[N+]=[N-])O[C@H]1N2C(NC(C=C2)=O)=O
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別名
4'-Azidouridine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : 100 mg/mL (350.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5062 mL | 17.5309 mL | 35.0619 mL | 87.6547 mL |
| 5 mM | 0.7012 mL | 3.5062 mL | 7.0124 mL | 17.5309 mL | |
| 10 mM | 0.3506 mL | 1.7531 mL | 3.5062 mL | 8.7655 mL | |
| 15 mM | 0.2337 mL | 1.1687 mL | 2.3375 mL | 5.8436 mL | |
| 20 mM | 0.1753 mL | 0.8765 mL | 1.7531 mL | 4.3827 mL | |
| 25 mM | 0.1402 mL | 0.7012 mL | 1.4025 mL | 3.5062 mL | |
| 30 mM | 0.1169 mL | 0.5844 mL | 1.1687 mL | 2.9218 mL | |
| 40 mM | 0.0877 mL | 0.4383 mL | 0.8765 mL | 2.1914 mL | |
| 50 mM | 0.0701 mL | 0.3506 mL | 0.7012 mL | 1.7531 mL | |
| 60 mM | 0.0584 mL | 0.2922 mL | 0.5844 mL | 1.4609 mL | |
| 80 mM | 0.0438 mL | 0.2191 mL | 0.4383 mL | 1.0957 mL | |
| 100 mM | 0.0351 mL | 0.1753 mL | 0.3506 mL | 0.8765 mL |
4'-C-Azidouridine 関連分類
HY-77650 関連分類
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