2-Azido-adenosine

Cat. No.: HY-151844 Purity: 99.59%: Data Sheet
COA

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2-Azido-adenosine is a click chemistry reagent containing an azide group. 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

2-Azido-adenosine Chemical Structure

CAS No. : 59587-07-4

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
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Description

2-Azido-adenosine is a click chemistry reagent containing an azide group^[1]. 2-Azido-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Molecular Weight

308.25

Formula

C₁₀H₁₂N₈O₄

CAS No.

59587-07-4

Appearance

Solid

Color

White to off-white

SMILES

NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=N2)=NC(N=[N+]=[N-])=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (324.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2441 mL	16.2206 mL	32.4412 mL
5 mM	0.6488 mL	3.2441 mL	6.4882 mL
10 mM	0.3244 mL	1.6221 mL	3.2441 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.59%

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Data Sheet (269 KB) SDS (252 KB)

COA (249 KB) HNMR (299 KB) RP-HPLC (258 KB) LCMS (286 KB)

Handling Instructions (2659 KB)

References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.2441 mL	16.2206 mL	32.4412 mL	81.1030 mL
	5 mM	0.6488 mL	3.2441 mL	6.4882 mL	16.2206 mL
	10 mM	0.3244 mL	1.6221 mL	3.2441 mL	8.1103 mL
	15 mM	0.2163 mL	1.0814 mL	2.1627 mL	5.4069 mL
	20 mM	0.1622 mL	0.8110 mL	1.6221 mL	4.0552 mL
	25 mM	0.1298 mL	0.6488 mL	1.2976 mL	3.2441 mL
	30 mM	0.1081 mL	0.5407 mL	1.0814 mL	2.7034 mL
	40 mM	0.0811 mL	0.4055 mL	0.8110 mL	2.0276 mL
	50 mM	0.0649 mL	0.3244 mL	0.6488 mL	1.6221 mL
	60 mM	0.0541 mL	0.2703 mL	0.5407 mL	1.3517 mL
	80 mM	0.0406 mL	0.2028 mL	0.4055 mL	1.0138 mL
	100 mM	0.0324 mL	0.1622 mL	0.3244 mL	0.8110 mL