Antibacterial agent 224
Antibacterial agent 224 is a potent and selective synthetic hydrazone inhibitor against the Salmonella PhoP/PhoQ system.
For research use only. We do not sell to patients.
- CAS No.: 16371-55-4
- Formula: C12H10N2OS
- Molecular Weight:230.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antibacterial agent 224 (compound A16B1) represses the Salmonella PhoP/PhoQ system activity, specifically targeting PhoQ within the second transmembrane region. Antibacterial agent 224 (compound A16B1) demonstrates synergy with the antimicrobial peptide colistin, reduces the intramacrophage proliferation of Salmonella without being cytotoxic and enhances the survival of G. mellonella larvae systemically infected with Salmonella[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16371-55-4
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Molecular Weight 230.29
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Formula C12H10N2OS
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SMILES
O=C(N/N=C/C1=CC=CS1)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)