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Cat. No.: HY-178455

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Influenza virus-IN-10

Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PA_C (K_D = 8.9 μM) and NP (K_D = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC₅₀ values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A.

For research use only. We do not sell to patients.

CAS No.: 3031321-95-3
Formula: C₂₆H₂₆N₄O₂
Molecular Weight:426.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Influenza virus-IN-10 Chemical Structure

CAS No.: 3031321-95-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Influenza virus-IN-10 (Compound 8e) shows inhibitory activity against A/HK/68 (IC₅₀ = 8.09 μM) and A/PR/8 (IC₅₀ = 7.54 μM)^[1].
Influenza virus-IN-10 remains stable after being incubated with proteinase K and mouse serum for 48 hours^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3031321-95-3
Molecular Weight 426.51
Formula C₂₆H₂₆N₄O₂
SMILES

O=C(C1=C(NC(CNC2=C(C)C=CC=C2)=O)C=CC=C1)NCCC3=C4C=CNC4=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang C, et al. Novel benzamide derivatives with indole moiety as dual-target antiviral agents: Rational design, efficient synthesis, and potent anti-influenza activity through concurrent binding to PAC terminal domain and viral nucleoprotein. Eur J Med Chem. 2025 Sep 5;293:117681. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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