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Cat. No.: HY-134321

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8-Azido-cAMP

8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP. 8-Azido-cAMP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

CAS No.: 31966-52-6
Formula: C₁₀H₁₁N₈O₆P
Molecular Weight:370.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

8-Azido-cAMP Chemical Structure

CAS No.: 31966-52-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP^[1]. 8-Azido-cAMP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Chemical Information

CAS No. 31966-52-6
Molecular Weight 370.22
Formula C₁₀H₁₁N₈O₆P
SMILES

[H][C@]([C@]1([H])O2)(OP(OC1)(O)=O)[C@@H](O)[C@]2([H])N3C4=NC=NC(N)=C4N=C3N=[N+]=[N-]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ito K, et al. Direct light-up of cAMP derivatives in living cells by click reactions. Molecules. 2013 Oct 17;18(10):12909-15 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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