1. Anti-infection
  2. Bacterial
  3. Thiocillin I

Thiocillin I 

Cat. No.: HY-125733
Handling Instructions

Thiocillin I is a thiopeptide antibiotic and has in vitro antibacterial activity against Gram-positive bacterial strains. The MIC values of Thiocillin I against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633 and S. pyogenes 1744264 are 2 μg/mL, 0.5 μg/mL, 4 μg/mL and 0.5 μg/mL, respectively.

For research use only. We do not sell to patients.

Thiocillin I Chemical Structure

Thiocillin I Chemical Structure

CAS No. : 59979-01-0

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Description

Thiocillin I is a thiopeptide antibiotic and has in vitro antibacterial activity against Gram-positive bacterial strains. The MIC values of Thiocillin I against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633 and S. pyogenes 1744264 are 2 μg/mL, 0.5 μg/mL, 4 μg/mL and 0.5 μg/mL, respectively[1].

IC50 & Target

Bacterial[1]

In Vitro

Thiocillin I (2 μM; 24 hours; U-2OS C3 osteosarcoma cells) is not proteasome inhibitor, and does not stabilize expression of multiple cellular proteins and suppresses FoxM1 expression in U-2OS C3 osteosarcoma cells[2].

Molecular Weight

1160.37

Formula

C₄₈H₄₉N₁₃O₁₀S₆

CAS No.

59979-01-0

SMILES

C[[email protected]](C(N1)C2=NC(C3=NC(C4=NC(C5=NC(C(N/C(C(NC[[email protected]](O)C)=O)=C\C)=O)=CS5)=CS4)=CC=C3C6=NC(C(N[[email protected]@](C(N/C(C7=NC(C(N[[email protected]@H](C(C)(O)C)C8=NC(C1=O)=CS8)=O)=CS7)=C\C)=O)([H])[[email protected]](O)C)=O)=CS6)=CS2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Thiocillin IBacterialInhibitorinhibitorinhibit

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Thiocillin I
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