2. Anti-infection
  3. Bacterial
  4. 1,3,7-Trihydroxy-2-prenylxanthone

1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum).

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1,3,7-Trihydroxy-2-prenylxanthone

1,3,7-Trihydroxy-2-prenylxanthone Chemical Structure

CAS No. : 20245-39-0

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1,3,7-Trihydroxy-2-prenylxanthone Related Antibodies

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Description

1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum)[1].

Cellular Effect
Cell Line Type Value Description References
HSC-2 CC50
> 0.64 mM
Compound: 9
Cytotoxicity against human HSC2 cells
Cytotoxicity against human HSC2 cells
[PMID: 11170668]
HepG2 IC50
> 10 μM
Compound: 15
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
[PMID: 24960143]
L02 IC50
> 10 μM
Compound: 15
Cytotoxicity against human HL7702 cells by MTT assay
Cytotoxicity against human HL7702 cells by MTT assay
[PMID: 24960143]
MCF7 IC50
> 10 μM
Compound: 15
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
[PMID: 24960143]
MDA-MB-231 IC50
> 10 μM
Compound: 15
Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
[PMID: 24960143]
RAW264.7 IC50
21.3 μM
Compound: 15
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma plus LPS-induced NO production
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma plus LPS-induced NO production
[PMID: 24960143]
Masse moléculaire

312.32

Formule

C18H16O5
CAS No.
SMILES

O=C1C2=C(OC3=C1C=C(O)C=C3)C=C(O)C(C/C=C(C)\C)=C2O
Structure Classification
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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1,3,7-Trihydroxy-2-prenylxanthone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,3,7-Trihydroxy-2-prenylxanthone20245-39-0BacterialxanthoneantibacterialVREsE. faecalisE. faeciumE. gallinarumInhibitorinhibitorinhibit

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