1,3,7-Trihydroxy-2-prenylxanthone
1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum).
For research use only. We do not sell to patients.
- CAS No.: 20245-39-0
- Formula: C18H16O5
- Molecular Weight:312.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>10 μM
Compound: 15
|
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
|
[PMID: 24960143] |
| HSC-2 | CC50 |
>0.64 mM
Compound: 9
|
Cytotoxicity against human HSC2 cells
Cytotoxicity against human HSC2 cells
|
[PMID: 11170668] |
| L02 | IC50 |
>10 μM
Compound: 15
|
Cytotoxicity against human HL7702 cells by MTT assay
Cytotoxicity against human HL7702 cells by MTT assay
|
[PMID: 24960143] |
| MCF7 | IC50 |
>10 μM
Compound: 15
|
Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
|
[PMID: 24960143] |
| MDA-MB-231 | IC50 |
>10 μM
Compound: 15
|
Cytotoxicity against human MDA-MB-231 cells by MTT assay
Cytotoxicity against human MDA-MB-231 cells by MTT assay
|
[PMID: 24960143] |
| RAW264.7 | IC50 |
21.3 μM
Compound: 15
|
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma plus LPS-induced NO production
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma plus LPS-induced NO production
|
[PMID: 24960143] |
Chemical Information
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CAS No. 20245-39-0
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Molecular Weight 312.32
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Formula C18H16O5
-
SMILES
O=C1C2=C(OC3=C1C=C(O)C=C3)C=C(O)C(C/C=C(C)\C)=C2O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)