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  4. DBCO-PEG3-Maleimide

DBCO-PEG3-Maleimide  (Synonyms: DBCO-NHCO-PEG3-maleimide)

Cat. No.: HY-W879049 Purity: 95.70%
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Handling Instructions Technical Support

DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group.

For research use only. We do not sell to patients.

DBCO-PEG3-Maleimide

DBCO-PEG3-Maleimide Chemical Structure

Size Price Stock Quantity
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Oil
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DBCO-PEG3-Maleimide:

DBCO-PEG3-Maleimide Related Antibodies

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Description

DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group[1].

Molecular Weight

630.69

Formula

C34H38N4O8
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCNC(CCN4C(C=CC4=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (158.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5856 mL 7.9278 mL 15.8557 mL
5 mM 0.3171 mL 1.5856 mL 3.1711 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5856 mL 7.9278 mL 15.8557 mL 39.6391 mL
5 mM 0.3171 mL 1.5856 mL 3.1711 mL 7.9278 mL
10 mM 0.1586 mL 0.7928 mL 1.5856 mL 3.9639 mL
15 mM 0.1057 mL 0.5285 mL 1.0570 mL 2.6426 mL
20 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9820 mL
25 mM 0.0634 mL 0.3171 mL 0.6342 mL 1.5856 mL
30 mM 0.0529 mL 0.2643 mL 0.5285 mL 1.3213 mL
40 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9910 mL
50 mM 0.0317 mL 0.1586 mL 0.3171 mL 0.7928 mL
60 mM 0.0264 mL 0.1321 mL 0.2643 mL 0.6607 mL
80 mM 0.0198 mL 0.0991 mL 0.1982 mL 0.4955 mL
100 mM 0.0159 mL 0.0793 mL 0.1586 mL 0.3964 mL
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DBCO-PEG3-Maleimide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DBCO-PEG3-MaleimideDBCO-NHCO-PEG3-maleimideBiochemical Assay ReagentsInhibitorinhibitorinhibit

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