Antimicrobial agent-46
Antimicrobial agent-46 is a inhibitor of Salmonella typhimurium serine acetyltransferase (StSAT) with an IC50 of 48.6 μM. Antimicrobial agent-46 inhibits bacterial growth in minimal medium lacking cysteine (LB 20%). Antimicrobial agent-46 exerts its effect by targeting the cysteine biosynthesis pathway, which is crucial for bacterial persistence and adaptability. Antimicrobial agent-46 exhibits antibacterial activity against the Gram-negative bacterium Escherichia coli. Antimicrobial agent-46 can be used in infection-related research .
For research use only. We do not sell to patients.
- CAS No.: 898619-81-3
- Formula: C6H3N5O3S2
- Molecular Weight:257.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antimicrobial agent-46 (for antibacterial tests, the maximum concentration is 128 μg/mL) inhibits Salmonella serine acetyltransferase and E. coli ATCC25922 growth in minimal LB 20% medium (IC50 = 48.6 μM for StSAT; MIC = 64 μg/mL for E. coli in LB 20%)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 898619-81-3
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Molecular Weight 257.25
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Formula C6H3N5O3S2
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SMILES
O=C(C1=CSN=N1)NC2=NC=C([N+]([O-])=O)S2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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