HIV-1-IN-92
HIV-1-IN-92 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase with an IC50 of 0.11 μM against HIV-1 reverse transcriptase. HIV-1-IN-92 exhibits activity against both wild-type HIV-1 IIIB and mutant HIV-1 strains. HIV-1-IN-92 can be used in research related to acquired immunodeficiency syndrome (AIDS).
For research use only. We do not sell to patients.
- Formula: C28H26N6O4S
- Molecular Weight:542.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HIV-1 |
HIV-1-IN-92 (Compound 29) (2-5 days) inhibits HIV-1 IIIB replication in MT-4 cells (EC50: 1.38 nM) and HIV-1 pNL4.3 replication in TZM-bl cells (EC50: 3.50 nM)[1].
HIV-1-IN-92 (5 days) inhibits the replication of multiple drug-resistant HIV-1 mutants in MT-4 cells, with EC50 values of 1.61 nM against the K103N mutant and 119 nM against the RES056 mutant[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 542.61
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Formula C28H26N6O4S
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SMILES
CC1=CC(/C=C/C#N)=CC(C)=C1OC2=C(COC3)C3=NC(NC4=CC(C#N)=C(N5CCS(CC5)(=O)=O)C=C4)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1-IN-92 Related Classifications
HY-181090 Related Classifications
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