Anti-Influenza agent 10
Based on 1 Customer Validation
Anti-Influenza agent 10 (Compound 41) is an influenza A virus RNA-dependent RNA polymerase (RdRp) inhibitor. Anti-Influenza agent 10 exhibits potent antiviral activity against A/PR/8/34(H1N1) with an IC50 of 0.29μM and a KD of 4.11 μM. Anti-Influenza agent 10 can inhibit the assembly of the viral RdRp complex by disrupting the protein interaction between PA and PB1 subunits, thereby blocking the transcription and replication of the viral genome. Anti-Influenza agent 10 shows significant broad-spectrum effects on multiple influenza virus strains, such as H3N2, H3N8 and H9N2 with IC50 values of 3.96, 1.91 and 1.45 μM. Anti-Influenza agent 10 can be used for the research of influenza A Virus Infection.
For research use only. We do not sell to patients.
- Formula: C25H23ClN4O2S
- Molecular Weight:478.99
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Anti-Infection Compound Library
HY-L002
-
Cell Cycle/DNA Damage Compound Library
HY-L004
-
Antiviral Compound Library
HY-L027
-
Anti-Aging Compound Library
HY-L034
-
MCE Bioactive Compound Library
HY-L001V
-
High-Throughput Bioactive Compound Library
HY-L205
All DNA/RNA Synthesis Isoforms
More
Biological Activity
|
RNA Polymerase |
Chemical Information
-
Appearance Solid
-
Molecular Weight 478.99
-
Formula C25H23ClN4O2S
-
Color White to off-white
-
SMILES
CC1=CC2=NC(C)=C(N2C=C1SCC(NC3=CC=C(C=C3)Cl)=O)C(NCC4=CC=CC=C4)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 101 mg/mL (210.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0877 mL | 10.4386 mL | 20.8773 mL | 52.1932 mL |
| 5 mM | 0.4175 mL | 2.0877 mL | 4.1755 mL | 10.4386 mL | |
| 10 mM | 0.2088 mL | 1.0439 mL | 2.0877 mL | 5.2193 mL | |
| 15 mM | 0.1392 mL | 0.6959 mL | 1.3918 mL | 3.4795 mL | |
| 20 mM | 0.1044 mL | 0.5219 mL | 1.0439 mL | 2.6097 mL | |
| 25 mM | 0.0835 mL | 0.4175 mL | 0.8351 mL | 2.0877 mL | |
| 30 mM | 0.0696 mL | 0.3480 mL | 0.6959 mL | 1.7398 mL | |
| 40 mM | 0.0522 mL | 0.2610 mL | 0.5219 mL | 1.3048 mL | |
| 50 mM | 0.0418 mL | 0.2088 mL | 0.4175 mL | 1.0439 mL | |
| 60 mM | 0.0348 mL | 0.1740 mL | 0.3480 mL | 0.8699 mL | |
| 80 mM | 0.0261 mL | 0.1305 mL | 0.2610 mL | 0.6524 mL | |
| 100 mM | 0.0209 mL | 0.1044 mL | 0.2088 mL | 0.5219 mL |
Anti-Influenza agent 10 Related Classifications
HY-180269 Related Classifications
Powered by Bioz