1. PROTAC
  2. PROTAC Linker
  3. PC Azido-PEG11-NHS carbonate ester

PC Azido-PEG11-NHS carbonate ester 

Cat. No.: HY-140142
Handling Instructions

PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

PC Azido-PEG11-NHS carbonate ester Chemical Structure

PC Azido-PEG11-NHS carbonate ester Chemical Structure

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Description

PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

993.02

Formula

C₄₂H₆₈N₆O₂₁

SMILES

O=C(CCCOC1=CC([N+]([O-])=O)=C(C(C)OC(ON2C(CCC2=O)=O)=O)C=C1OC)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PC Azido-PEG11-NHS carbonate esterPROTAC LinkerInhibitorinhibitorinhibit

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Product Name:
PC Azido-PEG11-NHS carbonate ester
Cat. No.:
HY-140142
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