8-Deazahomofolic acid
8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes. 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX (HY-14519) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors.
For research use only. We do not sell to patients.
- CAS No.: 111113-73-6
- Formula: C21H22N6O6
- Molecular Weight:454.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 111113-73-6
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Molecular Weight 454.44
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Formula C21H22N6O6
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SMILES
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCCC2=CC=C(C3=N2)NC(N)=NC3=O)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Deazahomofolic acid Related Classifications
HY-124093 Related Classifications
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