2. Anti-infection
  3. HIV
  4. HIV-1 inhibitor-22

HIV-1 inhibitor-22 (compound 11a) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 3.63 μM for HIV-1 RT. HIV-1 inhibitor-22 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 0.304 μM and 0.201 μM, also has low cytotoxicity (CC50 > 227 μM)

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HIV-1 inhibitor-22 Chemical Structure

HIV-1 inhibitor-22 Chemical Structure

CAS No. : 2554618-33-4

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HIV-1 inhibitor-22 Related Antibodies

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Description

HIV-1 inhibitor-22 (compound 11a) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 3.63 μM for HIV-1 RT. HIV-1 inhibitor-22 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 0.304 μM and 0.201 μM, also has low cytotoxicity (CC50 > 227 μM)[1]

IC50 & Target[1]

HIV-1 (WT)

0.304 μM (EC50)

HIV-1 (K103N)

0.201 μM (EC50)

Molecular Weight

550.63

Formula

C30H26N6O3S
CAS No.
SMILES

O=C(NC1=CC=C(C#N)C=C1)CSC2=NC(NC3=C(C)C=C(/C=C/C#N)C=C3C)=C4C=C(OC)C(OC)=CC4=N2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1 inhibitor-22 Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

HIV-1 inhibitor-222554618-33-4HIVHuman immunodeficiency virusAntiretroviralAnti-HIVAIDSHIV-1 K103NMT-4 cellsLow cytotoxicityInhibitorinhibitorinhibit

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