Antibacterial agent 96
Antibacterial agent 96 (compound 4k) is a potent antibacterial agent. Antibacterial agent 96 shows antitubercular activity against agent-susceptible and multidrug-resistantMycobacterium tuberculosis (M. tuberculosis) strains. Antibacterial agent 96 shows toxicity to HepG2 and Vero cells.
For research use only. We do not sell to patients.
- CAS No.: 2413006-62-7
- Formula: C18H15Cl2NO2
- Molecular Weight:348.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
14.4 μM
Compound: 4k
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 32113048] |
| HepG2 | CC50 |
14.9 μM
Compound: 4k
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
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[PMID: 32113048] |
| Vero | CC50 |
>20 μM
Compound: 4k
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 32113048] |
| Vero | CC50 |
>20 μM
Compound: 4k
|
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay
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[PMID: 32113048] |
Antibacterial agent 96 shows antibacterial activity with an MIC value of 0.3, 0.2, 0.5, 0.2, 14.4 μM for Mycobacterium tuberculosis (M. tuberculosis) H37RvPT2, PT12, PT20, qcrB-T313A strain, respectively[1].
Antibacterial agent 96 shows toxicity with CC50s of 14.4, >20 μM for HepG2 and Vero cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2413006-62-7
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Molecular Weight 348.22
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Formula C18H15Cl2NO2
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SMILES
COC1=CC2=C(N=C(C=C2OCC3=CC=C(C(Cl)=C3)Cl)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 96 Related Classifications
HY-146374 Related Classifications
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