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Art. -Nr.: HY-146374

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Antibacterial agent 96

Antibacterial agent 96 (compound 4k) is a potent antibacterial agent. Antibacterial agent 96 shows antitubercular activity against agent-susceptible and multidrug-resistantMycobacterium tuberculosis (M. tuberculosis) strains. Antibacterial agent 96 shows toxicity to HepG2 and Vero cells.

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CAS. Nr.: 2413006-62-7
Formel: C₁₈H₁₅Cl₂NO₂
Molecular Weight:348.22

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Antibacterial agent 96 Chemical Structure

CAS. Nr.: 2413006-62-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	CC₅₀	14.4 μM Compound: 4k	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32113048]
HepG2	CC₅₀	14.9 μM Compound: 4k	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay	[PMID: 32113048]
Vero	CC₅₀	>20 μM Compound: 4k	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32113048]
Vero	CC₅₀	>20 μM Compound: 4k	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by neutral red uptake assay	[PMID: 32113048]

In Vitro

Antibacterial agent 96 shows antibacterial activity with an MIC value of 0.3, 0.2, 0.5, 0.2, 14.4 μM for Mycobacterium tuberculosis (M. tuberculosis) H37RvPT2, PT12, PT20, qcrB-T313A strain, respectively^[1].
Antibacterial agent 96 shows toxicity with CC₅₀s of 14.4, >20 μM for HepG2 and Vero cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2413006-62-7
Molecular Weight 348.22
Formel C₁₈H₁₅Cl₂NO₂
SMILES

COC1=CC2=C(N=C(C=C2OCC3=CC=C(C(Cl)=C3)Cl)C)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. antibacterial; antitubercular; HepG2; Vero cells; Mycobacterium tuberculosis [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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