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4-Azido-L-phenylalanine

(Synonyms: p-Azidophenylalanine; p-Azido-L-phenylalanine)
10 Cited Publications
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Based on 10 publication(s) in Google Scholar

4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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  • Pureté : 99.93%
  • CAS No.: 33173-53-4
  • Formule: C9H10N4O2
  • Masse moléculaire:206.20
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • 4-Azido-L-phenylalanine Chemical Structure
    4-Azido-L-phenylalanine Chemical Structure
  • Experimental Validation Results for 4-Azido-L-phenylalanine
  • Experimental Validation Results for 4-Azido-L-phenylalanine
  • Experimental Validation Results for 4-Azido-L-phenylalanine
  • Experimental Validation Results for 4-Azido-L-phenylalanine
  • Experimental Validation Results for 4-Azido-L-phenylalanine
CAS No.: 33173-53-4
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  • 4-Azido-L-phenylalanine Chemical Structure
    4-Azido-L-phenylalanine Chemical Structure
    1/16
  • 1/16

    4-Azido-L-phenylalanine purchased from MedChemExpress. Usage Cited in: Nanomicro Lett. 2023 Aug 12;15(1):197. [Abstract]

    Customer Validation
     4-Azido-L-phenylalanine (Azi) (1 mM). The expression of mutated VSV-G proteins (mProteins) in HEK 293T cells was detected by Western blot.

  • 1/16

    4-Azido-L-phenylalanine purchased from MedChemExpress. Usage Cited in: Nanomicro Lett. 2023 Aug 12;15(1):197. [Abstract]

    Customer Validation
     The site-specific display of 4-Azido-L-phenylalanine (Azi) (1 mM) at site 192 in mProtein D192, as a typical site, was verified by LC-MS/MS spectrum of a peptide derived from the purified protein after trypsinization.

  • 1/16

    4-Azido-L-phenylalanine purchased from MedChemExpress. Usage Cited in: Nanomicro Lett. 2023 Aug 12;15(1):197. [Abstract]

    Customer Validation
     4-Azido-L-phenylalanine (Azi) (1 mM). The membrane proteins of mBiosomes were extracted and analyzed by Western blot.

  • 1/16

    4-Azido-L-phenylalanine purchased from MedChemExpress. Usage Cited in: Nanomicro Lett. 2023 Aug 12;15(1):197. [Abstract]

    Customer Validation
     The introduction of 4-Azido-L-phenylalanine (Azi) (1 mM) to site 246 caused evident changes in the secondary structures of the surrounding residues in mProtein A246.

  • 1/16

    4-Azido-L-phenylalanine purchased from MedChemExpress. Usage Cited in: Nanomicro Lett. 2023 Aug 12;15(1):197. [Abstract]

    Customer Validation
     4-Azido-L-phenylalanine (Azi) (1 mM). The proportion % of the secondary structures, including β-turn, helix, and random coil at surrounding sites (sites 245, 246, 247 and 248) in unmutated VSV-G, mProtein A246 and mProtein A247.

  • 4-Azido-L-phenylalanine