2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. N3-Gly-Gly-Gly-OH

N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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N3-Gly-Gly-Gly-OH

N3-Gly-Gly-Gly-OH 構造式

CAS 番号 : 1993176-75-2

容量 価格（税別） 在庫状況 数量
25 mg $188 在庫あり
50 mg $282 在庫あり
100 mg $438 在庫あり
250 mg $788 在庫あり
500 mg   お問い合わせ  
1 g   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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N3-Gly-Gly-Gly-OH 関連抗体

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製品説明

N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved[1][2][3]. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

分子量

215.17

分子式

C6H9N5O4
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCC(NCC(NCC(O)=O)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外: 

DMSO : 50 mg/mL (232.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6475 mL 23.2374 mL 46.4749 mL
5 mM 0.9295 mL 4.6475 mL 9.2950 mL
10 mM 0.4647 mL 2.3237 mL 4.6475 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.6475 mL 23.2374 mL 46.4749 mL 116.1872 mL
5 mM 0.9295 mL 4.6475 mL 9.2950 mL 23.2374 mL
10 mM 0.4647 mL 2.3237 mL 4.6475 mL 11.6187 mL
15 mM 0.3098 mL 1.5492 mL 3.0983 mL 7.7458 mL
20 mM 0.2324 mL 1.1619 mL 2.3237 mL 5.8094 mL
25 mM 0.1859 mL 0.9295 mL 1.8590 mL 4.6475 mL
30 mM 0.1549 mL 0.7746 mL 1.5492 mL 3.8729 mL
40 mM 0.1162 mL 0.5809 mL 1.1619 mL 2.9047 mL
50 mM 0.0929 mL 0.4647 mL 0.9295 mL 2.3237 mL
60 mM 0.0775 mL 0.3873 mL 0.7746 mL 1.9365 mL
80 mM 0.0581 mL 0.2905 mL 0.5809 mL 1.4523 mL
100 mM 0.0465 mL 0.2324 mL 0.4647 mL 1.1619 mL
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N3-Gly-Gly-Gly-OH Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N3-Gly-Gly-Gly-OH1993176-75-2ADC LinkerAntibody-drug conjugates linkerGly-Gly-Gly-Ser motifoligo-Glyalkyne-containing fragmentClick reactionInhibitorinhibitorinhibit

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製品名:
N3-Gly-Gly-Gly-OH
製品番号:
HY-151746
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