N3-Gly-Gly-Gly-OH
Based on 1 Customer Validation
N3-Gly-Gly-Gly-OH is a oligo-Gly click chemistry reagent containing an azide group. Oligo-Gly also has been used as linker to combine different subunits of dimeric or oligomeric proteins or to create artificial multi-domain proteins. By modification into Gly-Gly-Gly-Ser motifs high solubility can be achieved. N3-Gly-Gly-Gly-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity : 97.49%
- CAS No.: 1993176-75-2
- Formula: C6H9N5O4
- Molecular Weight:215.17
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1993176-75-2
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Appearance Solid
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Molecular Weight 215.17
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Formula C6H9N5O4
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Color White to off-white
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SMILES
[N-]=[N+]=NCC(NCC(NCC(O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (232.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Imanishi M, et al. DNA-bending finger: artificial design of 6-zinc finger peptides with polyglycine linker and induction of DNA bending. Biochemistry. 2000 Apr 18;39(15):4383-90. [Content Brief]
[2]. Tsygankova SV, et al. Biantennary oligoglycines and glyco-oligoglycines self-associating in aqueous medium. Beilstein J Org Chem. 2014 Jun 17;10:1372-82. [Content Brief]
[3]. Hashii N, et al. [Site-specific O-Glycosylation Analysis of Therapeutic Fc-fusion Protein by Mass Spectrometry]. Yakugaku Zasshi. 2018;138(12):1483-1494. Japanese. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6475 mL | 23.2374 mL | 46.4749 mL | 116.1872 mL |
| 5 mM | 0.9295 mL | 4.6475 mL | 9.2950 mL | 23.2374 mL | |
| 10 mM | 0.4647 mL | 2.3237 mL | 4.6475 mL | 11.6187 mL | |
| 15 mM | 0.3098 mL | 1.5492 mL | 3.0983 mL | 7.7458 mL | |
| 20 mM | 0.2324 mL | 1.1619 mL | 2.3237 mL | 5.8094 mL | |
| 25 mM | 0.1859 mL | 0.9295 mL | 1.8590 mL | 4.6475 mL | |
| 30 mM | 0.1549 mL | 0.7746 mL | 1.5492 mL | 3.8729 mL | |
| 40 mM | 0.1162 mL | 0.5809 mL | 1.1619 mL | 2.9047 mL | |
| 50 mM | 0.0929 mL | 0.4647 mL | 0.9295 mL | 2.3237 mL | |
| 60 mM | 0.0775 mL | 0.3873 mL | 0.7746 mL | 1.9365 mL | |
| 80 mM | 0.0581 mL | 0.2905 mL | 0.5809 mL | 1.4523 mL | |
| 100 mM | 0.0465 mL | 0.2324 mL | 0.4647 mL | 1.1619 mL |
N3-Gly-Gly-Gly-OH Related Classifications
HY-151746 Related Classifications
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