NNRT-IN-12
NNRT-IN-12 (compound 19) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor with an IC50 value of 0.107 μM for WT HIV-1 RT. NNRT-IN-12 shows anti-HIV-1 activity with EC50 value of 14.1, 5.03, 7.64, 27.1 nM for L100I, K103N, Y181C, Y188L mutant HIV-1 strains, respectively. NNRT-IN-12 shows cytotoxicity.
For research use only. We do not sell to patients.
- Formula: C30H28F2N6O2S
- Molecular Weight:574.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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RT-K103N 5.03 nM (EC50) |
RT-Y181C 7.64 nM (IC50) |
HIV-1 (L100I) 14.1 nM (EC50) |
RT-Y188L 27.1 nM (EC50) |
HIV-1 RT 0.107 μM (IC50) |
Chemical Information
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Molecular Weight 574.64
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Formula C30H28F2N6O2S
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SMILES
O=C(N)C1=CC=C(CN2CC(F)(F)C(NC3=NC(OC4=C(C)C=C(/C=C/C#N)C=C4C)=C5C(C=CS5)=N3)CC2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NNRT-IN-12 Related Classifications
HY-175667 Related Classifications
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