Echinosporin
Echinosporin (XK-213) is an antibiotic. Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity.
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- CAS. Nr.: 79127-35-8
- Formel: C10H9NO5
- Molecular Weight:223.18
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
MIC50: 64 μg/mL (Fusarium oxysporum); 64 μg/mL (Fusarium solani); 32 μg/mL (Alternaria panax); 64 μg/mL (Phoma herbarum)[2].
In Vitro
Echinosporin (XK-213) exhibits weak antibacterial activities against Gram-positive and -negative microorganisms and its shows antitumor activity[1].
Echinosporin exhibits antifungal activity against root-rot pathogens of Panax notoginseng include Fusarium oxysporum, Fusarium solani, Alternaria panax, and Phoma herbarum with the MIC50 value at 64, 64, 32, and 64 μg/mL, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 79127-35-8
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Molecular Weight 223.18
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Formel C10H9NO5
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SMILES
O=C(C1=C[C@@]([C@@](C(O2)=O)(O)C=C3)([H])[C@@]3([H])[C@@]2([H])O1)N
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Synonyms
XK-213
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Initial Source
streptomyces echinosporus MK-213
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. T Sato, et al. A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization. J Antibiot (Tokyo). 1982 Mar;35(3):266-71. [Content Brief]
[2]. Xindong Xu, et al. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiol (Praha). 2019 Mar;64(2):171-175. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Echinosporin Related Classifications
HY-113799 Related Classifications
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