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Cat. No.: HY-W008270R

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2(5H)-Furanone (Standard)

(Synonyms: γ-Crotonolactone (Standard))

2(5H)-Furanone (Standard) is the analytical standard of 2(5H)-Furanone. This product is intended for research and analytical applications. 2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2(5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2(5H)-Furanone inhibits biofilm formation of environmental Aeromonas hydrophila strains on polystyrene plates. 2(5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2(5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 497-23-4
Formula: C₄H₄O₂
Molecular Weight:84.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

2(5H)-Furanone (Standard) Chemical Structure

CAS No.: 497-23-4

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 497-23-4
Molecular Weight 84.07
Formula C₄H₄O₂
SMILES

O=C1OCC=C1
Synonyms

γ-Crotonolactone (Standard)
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Ahmed Hashem and Erich Kleinpeter, et al., The Chemistry of 2(5H)-Furanones, Advances in Heterocyclic Chemistry, Academic Press, Volume 81, 2001, Pages 107-165.

[2]. Sunil V. Pansare and Eldho K. Paul, Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes. RSC, Issue 3, 2011.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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