RSV-IN-6
RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC50 values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2415152-41-7
- Formula: C19H19N3S3
- Molecular Weight:385.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 1.3 μM (RSV-B), 4.4 μM (RSV-A)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | CC50 |
>100 μM
Compound: 53
|
Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
|
[PMID: 32143992] |
| HEp-2 | EC50 |
1.3 μM
Compound: 53
|
Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
|
[PMID: 32143992] |
| HEp-2 | EC50 |
4.4 μM
Compound: 53
|
Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
|
[PMID: 32143992] |
Chemical Information
-
CAS No. 2415152-41-7
-
Molecular Weight 385.57
-
Formula C19H19N3S3
-
SMILES
S=C(N1CCN(C2=CC=CC=C2)CC1)SCC3=NC4=CC=CC=C4S3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)