RSV-IN-6
RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC50 values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively.
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- No. CAS: 2415152-41-7
- Fòrmula: C19H19N3S3
- Peso molecular:385.57
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
EC50: 1.3 μM (RSV-B), 4.4 μM (RSV-A)[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEp-2 | CC50 |
>100 μM
Compound: 53
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Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay
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[PMID: 32143992] |
| HEp-2 | EC50 |
1.3 μM
Compound: 53
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Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
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[PMID: 32143992] |
| HEp-2 | EC50 |
4.4 μM
Compound: 53
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Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis
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[PMID: 32143992] |
Chemical Information
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No. CAS 2415152-41-7
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Peso molecular 385.57
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Fòrmula C19H19N3S3
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SMILES
S=C(N1CCN(C2=CC=CC=C2)CC1)SCC3=NC4=CC=CC=C4S3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RSV-IN-6 Related Classifications
HY-150547 Related Classifications
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