Etimicin

Etimicin (10 μg; 18 h) exhibits broad spectrum of activity against both gram positive and gram negative bacterial, with the highest activity against Klebsiella pneumoniae with a zone of inhibition of 31.29 mm^[1].
Etimicin (18-24 h) inhibits growth of typed bacterial strains with MIC values ranging from 0.125 to 0.5 mg/L, with the lowest potency against Acinetobacter baumanii MTCC-1425 (MIC = 0.5 mg/L) and highest potency against Proteus mirabilis MTCC-425, Salmonella typhi MTCC-535, and Escherichia coli MTCC-739 (MIC = 0.125 mg/L)^[1].
Etimicin (18-24 h) exerts bactericidal effects against typed bacterial strains with MBC values ranging from 0.25 to 2 mg/L, with the highest bactericidal potency against Escherichia coli MTCC-739 (MBC = 0.25 mg/L) and lowest potency against Acinetobacter baumanii MTCC-1425, Serratia grimesii MTCC-1887, Klebsiella pneumoniae MTCC-109, Enterobacter cloacae MTCC-509, and Staphylococcus aureus MTCC-737 (MBC = 2 mg/L)^[1].
Etimicin (18-24 h) inhibits growth of 279 aminoglycoside-susceptible clinical bacterial isolates with MIC₅₀ values ranging from 0.25 to 1 mg/L and MIC₉₀ values ranging from 1 to 4 mg/L, with the highest potency against Escherichia coli isolates (MIC₅₀ = 0.25 mg/L, MIC₉₀ = 1 mg/L)^[1].
Etimicin (18-24 h) inhibits growth of 128 aminoglycoside-resistant clinical bacterial isolates with MIC₅₀ values ranging from 2 to 4 mg/L and MIC₉₀ values ranging from 4 to 8 mg/L, with the highest potency against Escherichia coli, Klebsiella pneumoniae, and Staphylococcus species isolates (MIC₅₀ = 2 mg/L, MIC₉₀ = 4 mg/L)^[1].
Etimicin (0.125-0.25 mg/L; 2-12 h) at its MIC concentration exhibits rapid, sustained bactericidal activity against Escherichia coli MTCC-739, Klebsiella pneumoniae MTCC-109, Staphylococcus aureus MTCC-737, and Pseudomonas aeruginosa MTCC-1688, maintaining a 2-log reduction in viable cell count for 12 h without bacterial regrowth^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.