Azido Myristic Acid
Based on 1 Customer Validation
Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 80667-36-3
- Formula: C12H23N3O2
- Molecular Weight:241.33
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>50 μM
Compound: 12-Azidododecanoic acid
|
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo analysis
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo analysis
|
[PMID: 34583312] |
Azido Myristic Acid could be a suitable substrate for enzymes. Due to the very small size of the azide group and its complete absence in any natural molecules the presence of azide group does affect the biodistribution of azido palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 80667-36-3
-
Appearance Solid-Liquid Mixture
-
Molecular Weight 241.33
-
Formula C12H23N3O2
-
Color White to off-white
-
SMILES
[N-]=[N+]=NCCCCCCCCCCCC(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (414.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (265 KB)
-
SDS (795 KB)
- English - EN (795 KB)
- Français - FR (795 KB)
- Deutsch - DE (795 KB)
- Norwegian - NO (795 KB)
- Español - ES (795 KB)
- Swedish - SV (795 KB)
- Italian - IT (795 KB)
- Korean - KR (795 KB)
- Portuguese - PT (795 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1437 mL | 20.7185 mL | 41.4370 mL | 103.5926 mL |
| 5 mM | 0.8287 mL | 4.1437 mL | 8.2874 mL | 20.7185 mL | |
| 10 mM | 0.4144 mL | 2.0719 mL | 4.1437 mL | 10.3593 mL | |
| 15 mM | 0.2762 mL | 1.3812 mL | 2.7625 mL | 6.9062 mL | |
| 20 mM | 0.2072 mL | 1.0359 mL | 2.0719 mL | 5.1796 mL | |
| 25 mM | 0.1657 mL | 0.8287 mL | 1.6575 mL | 4.1437 mL | |
| 30 mM | 0.1381 mL | 0.6906 mL | 1.3812 mL | 3.4531 mL | |
| 40 mM | 0.1036 mL | 0.5180 mL | 1.0359 mL | 2.5898 mL | |
| 50 mM | 0.0829 mL | 0.4144 mL | 0.8287 mL | 2.0719 mL | |
| 60 mM | 0.0691 mL | 0.3453 mL | 0.6906 mL | 1.7265 mL | |
| 80 mM | 0.0518 mL | 0.2590 mL | 0.5180 mL | 1.2949 mL | |
| 100 mM | 0.0414 mL | 0.2072 mL | 0.4144 mL | 1.0359 mL |