Azidoacetic Acid
Based on 1 Customer Validation
Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 99.09%
- CAS No.: 18523-48-3
- Formula: C2H3N3O2
- Molecular Weight:101.06
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18523-48-3
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Appearance Liquid (Density: 1.350 g/cm3)
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Molecular Weight 101.06
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Formula C2H3N3O2
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Color Colorless to light yellow
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SMILES
[N-]=[N+]=NCC(O)=O
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Synonyms
2-Azidoacetic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (989.51 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (466 KB)
- English - EN (466 KB)
- Français - FR (466 KB)
- Deutsch - DE (466 KB)
- Norwegian - NO (466 KB)
- Español - ES (466 KB)
- Swedish - SV (466 KB)
- Italian - IT (466 KB)
- Korean - KR (466 KB)
- Portuguese - PT (466 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.8951 mL | 49.4756 mL | 98.9511 mL | 247.3778 mL |
| 5 mM | 1.9790 mL | 9.8951 mL | 19.7902 mL | 49.4756 mL | |
| 10 mM | 0.9895 mL | 4.9476 mL | 9.8951 mL | 24.7378 mL | |
| 15 mM | 0.6597 mL | 3.2984 mL | 6.5967 mL | 16.4919 mL | |
| 20 mM | 0.4948 mL | 2.4738 mL | 4.9476 mL | 12.3689 mL | |
| 25 mM | 0.3958 mL | 1.9790 mL | 3.9580 mL | 9.8951 mL | |
| 30 mM | 0.3298 mL | 1.6492 mL | 3.2984 mL | 8.2459 mL | |
| 40 mM | 0.2474 mL | 1.2369 mL | 2.4738 mL | 6.1844 mL | |
| 50 mM | 0.1979 mL | 0.9895 mL | 1.9790 mL | 4.9476 mL | |
| 60 mM | 0.1649 mL | 0.8246 mL | 1.6492 mL | 4.1230 mL | |
| 80 mM | 0.1237 mL | 0.6184 mL | 1.2369 mL | 3.0922 mL | |
| 100 mM | 0.0990 mL | 0.4948 mL | 0.9895 mL | 2.4738 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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