Bombacaceae

ABTL-0812 (α-Hydroxylinoleic acid) induces endoplasmic reticulum (ER) stress-mediated autophagy. ABTL-0812 is a first-in-class small molecule with anti-cancer activity.

Isohemigossylic acid lactone 2-methyl ether is a sesquiterpene lactone fungal inhibitor. Isohemigossylic acid lactone 2-methyl ether inhibits the conidial growth of Verticillium dahliae with a ED₅₀ of 7.8 μg/mL. Isohemigossylic acid lactone 2-methyl ether is isolated from the roots of Bombax malbaricum(synonym Salmalia malbaricum). Isohemigossylic acid lactone 2-methyl ether is applicable to studies related to Verticillium dahliae infection.

Hibiscolactone A is a 2H-naphtho[2,3-b]furan-2-one derivative and a superoxide anion generation inhibitor, which can be isolated from the stems of Pachira aquatica. The IC₅₀ value of Hibiscolactone A against fMLP (HY-P0224)-induced human neutrophil activity (inhibiting superoxide anion generation) is 63.22 μM.

Lacinilene C is a sesquiterpene-like compound isolated from the root of Bombax malabaricum.

Platyphyllenone is a narutal product that can be isolated from Alnus japonica.