HIV-1 inhibitor-59
HIV-1 inhibitor-59 (Compound I-5b) is a HIV-1 inhibitor, with EC50s of 5.62-171 nM against the wild-type (WT) and mutant HIV-1 strains. HIV-1 inhibitor-59 has moderate RT enzyme inhibitory activity (IC50: 0.094-12.0 μM).
For research use only. We do not sell to patients.
- Formula: C28H28FN5O3S
- Molecular Weight:533.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
27.5 μM
Compound: I-5b
|
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
|
[PMID: 37536208] |
Chemical Information
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Molecular Weight 533.62
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Formula C28H28FN5O3S
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SMILES
N#CC1=CC(C)=C(OC2=C(F)C=C(C#N)C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)=N2)C(C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)