N-Nitroso-tris-chloroethylurea
N-nitroso-tris-chloroethylurea (NTCU) can be used for chemically inducing a lung squamous cell carcinoma model. Lung squamous cell carcinoma can be induced in five mouse strains (SWR/J, NIH Swiss, A/J, BALB/cJ, and FVB/J) by applying N-nitroso-tris-chloroethylurea to the skin, but not in the other three strains (AKR/J, 129/svJ, and C57BL/6J) .
For research use only. We do not sell to patients.
- CAS No.: 69113-01-5
- Formula: C7H12Cl3N3O2
- Molecular Weight:276.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 69113-01-5
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Molecular Weight 276.55
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Formula C7H12Cl3N3O2
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SMILES
O=NN(CCCl)C(N(CCCl)CCCl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hudish TM, Opincariu LI, Mozer AB, et al. N-nitroso-tris-chloroethylurea induces premalignant squamous dysplasia in mice. Cancer Prev Res (Phila). 2012;5(2):283-289. [Content Brief]
[2]. Wang Y, Zhang Z, Yan Y, et al. A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility. Cancer Res. 2004;64(5):1647-1654. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Nitroso-tris-chloroethylurea Related Classifications
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