D-Asparagine
Based on 1 Customer Validation
D-Asparagine (H-D-Asn-OH) acts as a competitive inhibitor of L-asparagine hydrolysis, with a Ki value of 0.24 mM. D-Asparagine serves as a nitrogen source for yeast strains. D-Asparagine is a good substrate for external yeast asparaginase but a poor substrate for internal yeast asparaginase.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2058-58-4
- Formula: C4H8N2O3
- Molecular Weight:132.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
D-Asparagine (2-10 mM; 48 h, generation time measured at 21°C) can serve as the sole nitrogen source for growth in extracellular asparaginase-secreting Saccharomyces cerevisiae strains (D273-10B, X2180-A2) and their gap-1 mutants[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2058-58-4
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Appearance Solid
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Molecular Weight 132.12
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Formula C4H8N2O3
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Color White to off-white
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SMILES
N[C@H](CC(N)=O)C(O)=O
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Synonyms
H-D-Asn-OH
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 33.33 mg/mL (252.27 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Dunlop PC, et al. Utilization of D-asparagine by Saccharomyces cerevisiae. J Bacteriol. 1976;125(3):999-1004. [Content Brief]
[2]. Taniguchi A, et al. D-Asparagine is an Ideal Endogenous Molecule for Measuring the Glomerular Filtration Rate. Kidney Int Rep. 2023;8(6):1192-1200. Published 2023 Mar 21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.5689 mL | 37.8444 mL | 75.6888 mL | 189.2219 mL |
| 5 mM | 1.5138 mL | 7.5689 mL | 15.1378 mL | 37.8444 mL | |
| 10 mM | 0.7569 mL | 3.7844 mL | 7.5689 mL | 18.9222 mL | |
| 15 mM | 0.5046 mL | 2.5230 mL | 5.0459 mL | 12.6148 mL | |
| 20 mM | 0.3784 mL | 1.8922 mL | 3.7844 mL | 9.4611 mL | |
| 25 mM | 0.3028 mL | 1.5138 mL | 3.0276 mL | 7.5689 mL | |
| 30 mM | 0.2523 mL | 1.2615 mL | 2.5230 mL | 6.3074 mL | |
| 40 mM | 0.1892 mL | 0.9461 mL | 1.8922 mL | 4.7305 mL | |
| 50 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7844 mL | |
| 60 mM | 0.1261 mL | 0.6307 mL | 1.2615 mL | 3.1537 mL | |
| 80 mM | 0.0946 mL | 0.4731 mL | 0.9461 mL | 2.3653 mL | |
| 100 mM | 0.0757 mL | 0.3784 mL | 0.7569 mL | 1.8922 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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