2. Immunology/Inflammation
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  4. Peonidin chloride

Peonidin chloride  (Synonyms: YGM-6 chloride)

Cat. No.: HY-N2459 Purity: 98.70%
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Peonidin chloride is an O-methylated anthocyanidin that functions as a primary plant pigment, endowing purplish-red hues to flowers such as the peony, from which it takes its name, as well as berries and vegetables. Peonidin chloride exhibits chemopreventive, as well as anti-inflammatory activities on cancer cells in vitro, blocking COX-2 expression and transformation in JB6 P+ mouse epidermal cells.

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Peonidin chloride Chemical Structure

Peonidin chloride Chemical Structure

CAS No. : 134-01-0

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Based on 1 publication(s) in Google Scholar

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Description

Peonidin chloride is an O-methylated anthocyanidin that functions as a primary plant pigment, endowing purplish-red hues to flowers such as the peony, from which it takes its name, as well as berries and vegetables. Peonidin chloride exhibits chemopreventive, as well as anti-inflammatory activities on cancer cells in vitro, blocking COX-2 expression and transformation in JB6 P+ mouse epidermal cells.

IC50 & Target

COX-2

 

Molecular Weight

336.72

Formula

C16H13ClO6
CAS No.
Appearance

Solid

Color

Brown to black

SMILES

COC1=CC(C2=C(O)C=C3C(C=C(O)C=C3O)=[O+]2)=CC=C1O.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (296.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9698 mL 14.8491 mL 29.6983 mL
5 mM 0.5940 mL 2.9698 mL 5.9397 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9698 mL 14.8491 mL 29.6983 mL 74.2457 mL
5 mM 0.5940 mL 2.9698 mL 5.9397 mL 14.8491 mL
10 mM 0.2970 mL 1.4849 mL 2.9698 mL 7.4246 mL
15 mM 0.1980 mL 0.9899 mL 1.9799 mL 4.9497 mL
20 mM 0.1485 mL 0.7425 mL 1.4849 mL 3.7123 mL
25 mM 0.1188 mL 0.5940 mL 1.1879 mL 2.9698 mL
30 mM 0.0990 mL 0.4950 mL 0.9899 mL 2.4749 mL
40 mM 0.0742 mL 0.3712 mL 0.7425 mL 1.8561 mL
50 mM 0.0594 mL 0.2970 mL 0.5940 mL 1.4849 mL
60 mM 0.0495 mL 0.2475 mL 0.4950 mL 1.2374 mL
80 mM 0.0371 mL 0.1856 mL 0.3712 mL 0.9281 mL
100 mM 0.0297 mL 0.1485 mL 0.2970 mL 0.7425 mL
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Peonidin chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peonidin134-01-0YGM-6YGM6YGM 6COXCyclooxygenaseInhibitorinhibitorinhibit

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