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Cat. No.: HY-133402

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BCN-exo-PEG3-NH2

Name: BCN-exo-PEG3-NH2
Brand: MedChemExpress
SKU: HY-133402
Price: 230.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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BCN- exo- PEG3- NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. BCN- exo- PEG3- NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Purity: 99.94%
CAS No.: 1841134-72-2
Formula: C₁₉H₃₂N₂O₅
Molecular Weight:368.47

Storage:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

BCN-exo-PEG3-NH2 Chemical Structure

CAS No.: 1841134-72-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BCN- exo- PEG3- NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1]. BCN- exo- PEG3- NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC₅₀ & Target

PEGs

All PROTAC Linkers Isoforms :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1841134-72-2
Appearance Liquid (Density: 1.14±0.1 g/cm³)
Molecular Weight 368.47
Formula C₁₉H₃₂N₂O₅
Color Colorless to light yellow
SMILES

NCCOCCOCCOCCNC(OC[C@@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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BCN-​exo-​PEG3-​NH2

All PROTAC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BCN-​exo-​PEG3-​NH2 Related Classifications

HY-133402 Related Classifications

Bioz

BCN-exo-PEG3-NH2

BCN-exo-PEG3-NH2 Related Classifications