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  3. Cholesterol-PEG3-azide

Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

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Cholesterol-PEG3-azide

Cholesterol-PEG3-azide Chemical Structure

CAS No. : 1459756-73-0

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Based on 1 publication(s) in Google Scholar

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Description

Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

686.96

Formula

C39H66N4O6

CAS No.
Appearance

Oil

Color

Colorless to off-white

SMILES

[H][C@@]12CC=C3C[C@H](CC[C@@]3([C@]1(CC[C@]4([C@]2(CC[C@@]4([C@@H](CCCC(C)C)C)[H])[H])C)[H])C)OC(CCC(NCCOCCOCCOCCN=[N+]=[N-])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (145.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4557 mL 7.2784 mL 14.5569 mL
5 mM 0.2911 mL 1.4557 mL 2.9114 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4557 mL 7.2784 mL 14.5569 mL 36.3922 mL
5 mM 0.2911 mL 1.4557 mL 2.9114 mL 7.2784 mL
10 mM 0.1456 mL 0.7278 mL 1.4557 mL 3.6392 mL
15 mM 0.0970 mL 0.4852 mL 0.9705 mL 2.4261 mL
20 mM 0.0728 mL 0.3639 mL 0.7278 mL 1.8196 mL
25 mM 0.0582 mL 0.2911 mL 0.5823 mL 1.4557 mL
30 mM 0.0485 mL 0.2426 mL 0.4852 mL 1.2131 mL
40 mM 0.0364 mL 0.1820 mL 0.3639 mL 0.9098 mL
50 mM 0.0291 mL 0.1456 mL 0.2911 mL 0.7278 mL
60 mM 0.0243 mL 0.1213 mL 0.2426 mL 0.6065 mL
80 mM 0.0182 mL 0.0910 mL 0.1820 mL 0.4549 mL
100 mM 0.0146 mL 0.0728 mL 0.1456 mL 0.3639 mL
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Cholesterol-PEG3-azide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cholesterol-PEG3-azide
Cat. No.:
HY-174924
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