Azido-PEG8-NHBoc
Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-NHBoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2231845-12-6
- 分子式: C23H46N4O10
- 分子量:538.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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PEGs |
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2231845-12-6
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分子量 538.63
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分子式 C23H46N4O10
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SMILES
O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)