1. PROTAC
  2. PROTAC Linker

N33-TEG-COOH (Synonyms: N3-TEG-COOH; 14-Azido-3,6,9,12-tetraoxatetradecanoic acid)

Cat. No.: HY-108370 Purity: >96.0%
Handling Instructions

N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.

For research use only. We do not sell to patients.

N33-TEG-COOH Chemical Structure

N33-TEG-COOH Chemical Structure

CAS No. : 201467-81-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

N33-TEG-COOH is a PROTAC linker containing four polyethylene glycol (PEG) units.

IC50 & Target

PROTAC linker[1]

In Vitro

N33-TEG-COOH is a long linker extracted from Reference PMID: 26035625, Compound 7. A PROTAC is a heterobifunctional compound that contains two ligands connected by a linker unit. One ligand binds an E3 ubiquitin ligase protein, while the other ligand binds to the target protein of interest, thereby bringing the ligase and the target in close proximity[1].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (360.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6066 mL 18.0330 mL 36.0659 mL
5 mM 0.7213 mL 3.6066 mL 7.2132 mL
10 mM 0.3607 mL 1.8033 mL 3.6066 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

277.27

Formula

C₁₀H₁₉N₃O₆

CAS No.

201467-81-4

SMILES

O=C(O)COCCOCCOCCOCCN=[N+]=[N-]

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
N33-TEG-COOH
Cat. No.:
HY-108370
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N33-TEG-COOH

Cat. No.: HY-108370