8,9-Dehydro-7,9-diisobutyryloxythymol
8,9-Dehydro-7,9-diisobutyryloxythymol is a Thymol (HY-N6810) derivative, as well as an antibacterial agent. 8,9-Dehydro-7,9-diisobutyryloxythymol can be found in the aerial parts of Ageratina adenophora, with selective activity against Gram-positive bacterial strains including Bacillus cereus. 8,9-Dehydro-7,9-diisobutyryloxythymol does not exhibit detectable in vitro cytotoxic activity against human cancer cell lines. 8,9-Dehydro-7,9-diisobutyryloxythymol can be used for the research of bacterial infection.
For research use only. We do not sell to patients.
- CAS No.: 22518-03-2
- Formula: C18H24O5
- Molecular Weight:320.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
8,9-Dehydro-7,9-diisobutyryloxythymol (compound 2) (1.0 mg/mL initial concentration with serial doubling dilution; 5-6 h) selectively exhibits antibacterial activity against B. cereus with a MIC of 62.5 μg/mL and no activity against S. aureus, B. thuringiensis, E. coli, or S. enterica[1].
8,9-Dehydro-7,9-diisobutyryloxythymol (compound 2) (1.5625-50 μg/mL; 3 days) does not exhibit cytotoxic activity against MCF-7, NCI-H460, or HeLa cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7, NCI-H460, HeLa
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Concentration:1.5625-50 μg/mL
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Incubation Time:3 days
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Result:Detected no obvious cytotoxic activity; Recorded IC50 >100 μM against MCF-7, NCI-H460, and HeLa cell lines.
Chemical Information
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CAS No. 22518-03-2
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Molecular Weight 320.38
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Formula C18H24O5
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SMILES
O=C(C(C)C)O/C=C(C)/C1=CC=C(COC(C(C)C)=O)C=C1O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8,9-Dehydro-7,9-diisobutyryloxythymol Related Classifications
HY-N13838 Related Classifications
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Keywords
- 8,9-Dehydro-7,9-diisobutyryloxythymol
- 22518-03-2
- Bacterial
- Bacillus cereus
- Gram-positive bacterial strains
- Ageratina adenophora
- bacillus thuringiensis infection
- bacillus cereus infection
- Staphylococcus aureus
- Bacillus thuringiensis
- human cancer cell lines
- staphylococcus aureus infection
- MCF-7
- Inhibitor
- inhibitor
- inhibit