2. Anti-infection
  3. Bacterial
  4. 8,9-Dehydro-7,9-diisobutyryloxythymol

8,9-Dehydro-7,9-diisobutyryloxythymol is a Thymol (HY-N6810) derivative, as well as an antibacterial agent. 8,9-Dehydro-7,9-diisobutyryloxythymol can be found in the aerial parts of Ageratina adenophora, with selective activity against Gram-positive bacterial strains including Bacillus cereus. 8,9-Dehydro-7,9-diisobutyryloxythymol does not exhibit detectable in vitro cytotoxic activity against human cancer cell lines. 8,9-Dehydro-7,9-diisobutyryloxythymol can be used for the research of bacterial infection.

For research use only. We do not sell to patients.

8,9-Dehydro-7,9-diisobutyryloxythymol

8,9-Dehydro-7,9-diisobutyryloxythymol Chemical Structure

CAS No. : 22518-03-2

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8,9-Dehydro-7,9-diisobutyryloxythymol Related Antibodies

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Description

8,9-Dehydro-7,9-diisobutyryloxythymol is a Thymol (HY-N6810) derivative, as well as an antibacterial agent. 8,9-Dehydro-7,9-diisobutyryloxythymol can be found in the aerial parts of Ageratina adenophora, with selective activity against Gram-positive bacterial strains including Bacillus cereus. 8,9-Dehydro-7,9-diisobutyryloxythymol does not exhibit detectable in vitro cytotoxic activity against human cancer cell lines. 8,9-Dehydro-7,9-diisobutyryloxythymol can be used for the research of bacterial infection[1].

In Vitro

8,9-Dehydro-7,9-diisobutyryloxythymol (compound 2) (1.0 mg/mL initial concentration with serial doubling dilution; 5-6 h) selectively exhibits antibacterial activity against B. cereus with a MIC of 62.5 μg/mL and no activity against S. aureus, B. thuringiensis, E. coli, or S. enterica[1].
8,9-Dehydro-7,9-diisobutyryloxythymol (compound 2) (1.5625-50 μg/mL; 3 days) does not exhibit cytotoxic activity against MCF-7, NCI-H460, or HeLa cell lines[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

8,9-Dehydro-7,9-diisobutyryloxythymol Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: MCF-7, NCI-H460, HeLa
Concentration: 1.5625-50 μg/mL
Incubation Time: 3 days
Result: Detected no obvious cytotoxic activity; Recorded IC50 >100 μM against MCF-7, NCI-H460, and HeLa cell lines.
Molecular Weight

320.38

Formula

C18H24O5
CAS No.
SMILES

O=C(C(C)C)O/C=C(C)/C1=CC=C(COC(C(C)C)=O)C=C1O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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8,9-Dehydro-7,9-diisobutyryloxythymol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8,9-Dehydro-7,9-diisobutyryloxythymol22518-03-2BacterialBacillus cereusGram-positive bacterial strainsAgeratina adenophorabacillus thuringiensis infectionbacillus cereus infectionStaphylococcus aureusBacillus thuringiensishuman cancer cell linesstaphylococcus aureus infectionMCF-7Inhibitorinhibitorinhibit

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