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Art. -Nr.: HY-133735

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GRP-60367

Name: GRP-60367
Brand: MedChemExpress
SKU: HY-133735
Price: 100.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

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GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 98.23%
CAS. Nr.: 1309241-34-6
Formel: C₂₁H₂₇N₃O₂
Molecular Weight:353.46

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

GRP-60367 Chemical Structure

CAS. Nr.: 1309241-34-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
Chemical Information
Publications (1)
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Biologische Aktivität

Beschreibung

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains^[1].

In Vitro

GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC₅₀s ranging from 2 to 52 nM on different host cell lines^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1309241-34-6
Appearance Solid
Molecular Weight 353.46
Formel C₂₁H₂₇N₃O₂
Color White to off-white
SMILES

CC1=C(OCCNC2CCN(C(C3=CC=NC=C3)=O)CC2)C=C(C)C=C1
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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Antiviral Res

β-d-N4-hydroxycytidine, a metabolite of molnupiravir, exhibits in vitro antiviral activity against rabies virus. [Abstract]

2024 Sep:229:105977. PMID: 39089332

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Venice Du Pont, et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor. J Virol. 2020 Jun 16;94(13):e00321-20. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

GRP-60367

1 Cited Publications

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Biologische Aktivität
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Chemical Information
Publications (1)
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GRP-60367

Publications Citing Use of MedChemExpress (MCE) GRP-60367

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Chemical Information

Publications (1)

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GRP-60367 Related Classifications

HY-133735 Related Classifications

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