Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells.
For research use only. We do not sell to patients.
- Formula: C20H12ClN3O5
- Molecular Weight:409.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MIC: 0.03 µg/mL in DS-Mtb, 0.03-0.06 µg/mL in DR-Mtb[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
5 μg/mL
Compound: 6xa
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 35487101] |
Chemical Information
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Molecular Weight 409.78
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Formula C20H12ClN3O5
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SMILES
O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitubercular agent-29 Related Classifications
HY-150554 Related Classifications
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