2. Anti-infection
  3. Bacterial Antibiotic
  4. TBT1

TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM.

For research use only. We do not sell to patients.

TBT1 Chemical Structure

TBT1 Chemical Structure

CAS No. : 52535-76-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 308 In-stock
Solution
10 mM * 1 mL in DMSO USD 308 In-stock
Solid
5 mg USD 280 In-stock
10 mg USD 450 In-stock
50 mg USD 1350 In-stock
100 mg USD 2150 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

TBT1 Related Antibodies

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Description

TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM[1].

Molecular Weight

335.81

Formula

C16H14ClNO3S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=C(NC(C2=CC=C(Cl)C=C2)=O)SC3=C1CCCC3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (372.23 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9779 mL 14.8894 mL 29.7787 mL
5 mM 0.5956 mL 2.9779 mL 5.9557 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9779 mL 14.8894 mL 29.7787 mL 74.4469 mL
5 mM 0.5956 mL 2.9779 mL 5.9557 mL 14.8894 mL
10 mM 0.2978 mL 1.4889 mL 2.9779 mL 7.4447 mL
15 mM 0.1985 mL 0.9926 mL 1.9852 mL 4.9631 mL
20 mM 0.1489 mL 0.7445 mL 1.4889 mL 3.7223 mL
25 mM 0.1191 mL 0.5956 mL 1.1911 mL 2.9779 mL
30 mM 0.0993 mL 0.4963 mL 0.9926 mL 2.4816 mL
40 mM 0.0744 mL 0.3722 mL 0.7445 mL 1.8612 mL
50 mM 0.0596 mL 0.2978 mL 0.5956 mL 1.4889 mL
60 mM 0.0496 mL 0.2482 mL 0.4963 mL 1.2408 mL
80 mM 0.0372 mL 0.1861 mL 0.3722 mL 0.9306 mL
100 mM 0.0298 mL 0.1489 mL 0.2978 mL 0.7445 mL
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TBT1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TBT152535-76-9TBT 1TBT-1BacterialAntibioticfirst-generationMsbA transporterAcinetobacterInhibitorinhibitorinhibit

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