NNRT-IN-2
NNRT-IN-2 (compound 7w) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains. NNRT-IN-2 inhibits HIV-1 reverse transcriptase with an EC50 of 22 nM. NNRT-IN-2 is insensitive to CYP and hERG and has good safety and pharmacokinetic characteristics.
For research use only. We do not sell to patients.
- CAS No.: 2999794-78-2
- Formula: C19H14F3N5O3
- Molecular Weight:417.34
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 22 nM (HIV Reverse Transcriptase)[1]
Chemical Information
-
CAS No. 2999794-78-2
-
Molecular Weight 417.34
-
Formula C19H14F3N5O3
-
SMILES
CN1C(NN=C1CN2C=CC(C(F)(F)F)=C(C2=O)OC3=C4C=CN=CC4=CC=C3)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)