2. Anti-infection
  3. Bacterial
  4. PA3552-IN-1

PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression.

For research use only. We do not sell to patients.

PA3552-IN-1 Chemical Structure

PA3552-IN-1 Chemical Structure

CAS No. : 1008121-12-7

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Solid + Solvent
10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 77 In-stock
Solid
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Based on 1 publication(s) in Google Scholar

PA3552-IN-1 Related Antibodies

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Description

PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression[1].

Molecular Weight

310.67

Formula

C13H8ClFN2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(C=CC(F)=C1)O)NC2=CC=C(C=C2Cl)[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 13.89 mg/mL (44.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2188 mL 16.0942 mL 32.1885 mL
5 mM 0.6438 mL 3.2188 mL 6.4377 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.55%

COA (248 KB) HNMR (277 KB) LCMS (270 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2188 mL 16.0942 mL 32.1885 mL 80.4712 mL
5 mM 0.6438 mL 3.2188 mL 6.4377 mL 16.0942 mL
10 mM 0.3219 mL 1.6094 mL 3.2188 mL 8.0471 mL
15 mM 0.2146 mL 1.0729 mL 2.1459 mL 5.3647 mL
20 mM 0.1609 mL 0.8047 mL 1.6094 mL 4.0236 mL
25 mM 0.1288 mL 0.6438 mL 1.2875 mL 3.2188 mL
30 mM 0.1073 mL 0.5365 mL 1.0729 mL 2.6824 mL
40 mM 0.0805 mL 0.4024 mL 0.8047 mL 2.0118 mL
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PA3552-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PA3552-IN-11008121-12-7Bacterialantibiotic adjuvantMDRP. aeruginosaDK2PA3552Inhibitorinhibitorinhibit

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