InhA-IN-7
InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM.
For research use only. We do not sell to patients.
- CAS No.: 952588-17-9
- Formula: C17H18Cl2O2
- Molecular Weight:325.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
96 nM (InhA)
Chemical Information
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CAS No. 952588-17-9
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Molecular Weight 325.23
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Formula C17H18Cl2O2
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SMILES
ClC1=CC=C(C(Cl)=C1)OC2=CC=C(CCC(C)C)C=C2O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)