Luteolin-3′,7-diglucoside
Based on 1 Customer Validation
Luteolin-3′,7-diglucoside is a glycoside that can be isolated from R. luteolin. Luteolin-3′,7-diglucoside significantly inhibits cataracts induced in ovine lenses. Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticumATCC and clinical strains.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 52187-80-1
- Formula: C27H30O16
- Molecular Weight:610.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATCC and clinical strains of Ureaplasma urealyticum[3]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Monocyte | IC50 |
1.55 μM
Compound: luteolin-3',7-diglucoside
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Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
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[PMID: 8882428] |
| Monocyte | IC50 |
1.55 x 10-6 M
Compound: luteolin-3',7-diglucoside
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Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
Inhibition of procoagulant activity in monocyte from human blood assessed as counteraction of IL1-induced tissue factor expression after 18 hrs
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[PMID: 8882428] |
Luteolin-3′,7-diglucoside (10 µM; 24 h) significantly inhibits cataracts induced in ovine lenses incubated in 45 % hypotonic hepes buffered solution (HBS) for 24 h[2].
Luteolin-3′,7-diglucoside inhibits the activity of Ureaplasma urealyticum ATCC strains (MIC range=7.8-15.6 µM) and Ureaplasma urealyticum clinical strains (MIC range=0.48-1.95 µM)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 52187-80-1
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Appearance Solid
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Molecular Weight 610.52
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Formula C27H30O16
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Color Light yellow to yellow
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SMILES
O=C1C(C(OC(C(C=C2)=CC(O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)=C2O)=C1)=CC(O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)=C5)=C5O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (81.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6379 mL | 8.1897 mL | 16.3795 mL | 40.9487 mL |
| 5 mM | 0.3276 mL | 1.6379 mL | 3.2759 mL | 8.1897 mL | |
| 10 mM | 0.1638 mL | 0.8190 mL | 1.6379 mL | 4.0949 mL | |
| 15 mM | 0.1092 mL | 0.5460 mL | 1.0920 mL | 2.7299 mL | |
| 20 mM | 0.0819 mL | 0.4095 mL | 0.8190 mL | 2.0474 mL | |
| 25 mM | 0.0655 mL | 0.3276 mL | 0.6552 mL | 1.6379 mL | |
| 30 mM | 0.0546 mL | 0.2730 mL | 0.5460 mL | 1.3650 mL | |
| 40 mM | 0.0409 mL | 0.2047 mL | 0.4095 mL | 1.0237 mL | |
| 50 mM | 0.0328 mL | 0.1638 mL | 0.3276 mL | 0.8190 mL | |
| 60 mM | 0.0273 mL | 0.1365 mL | 0.2730 mL | 0.6825 mL | |
| 80 mM | 0.0205 mL | 0.1024 mL | 0.2047 mL | 0.5119 mL |
Luteolin-3′,7-diglucoside Related Classifications
HY-N8318 Related Classifications
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