Wychimicin A
Wychimicin A is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin A shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL).
For research use only. We do not sell to patients.
- Formula: C47H60ClNO11
- Molecular Weight:850.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 850.43
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Formula C47H60ClNO11
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SMILES
CC1=CC(Cl)=C(C(C(N[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@]([H])(C/C=C/C3[C@@]4([C@]5([C@]([H])(C=C3CC)[C@H]([C@H](C[C@@H]5C)O)O)[H])C)/C(C)=C/[C@H]6[C@]7(C[C@@H](C=C6)C)C(O)=C(C(O7)=O)C4=O)C)=O)=C1O)C
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Structure Classification
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Initial Source
Actinocrispum wychmicini
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kimura T, et al. Wychimicins, a new class of spirotetronate polyketides from Actinocrispum wychmicini MI503-A4. J Antibiot (Tokyo). 2022 Oct;75(10):535-541. [Content Brief]
[2]. Hatano M, et al. Actinocrispum wychmicini gen. nov., sp. nov., a novel member of the family Pseudonocardiaceae, isolated from soil. Int J Syst Evol Microbiol. 2016 Nov;66(11):4779-4784. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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