Antibacterial agent 240
Antibacterial agent 240 (compound 62-7c) is an antibacterial agent that can target multidrug-resistant (MDR) MRSA strains. Antibacterial agent 240 showed high biosafety and potent anti-infection activity in mouse pneumonia and mouse wound models of MRSA infection.
For research use only. We do not sell to patients.
- CAS No.: 2899202-97-0
- Formula: C28H18ClN3O5S2
- Molecular Weight:576.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
MRSA[1]
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LX-2 | CC50 |
>100 μM
Compound: 62-7c
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Cytotoxicity against human LX2 cells incubated for 24 hrs by CCK8 assay
Cytotoxicity against human LX2 cells incubated for 24 hrs by CCK8 assay
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[PMID: 39208742] |
Chemical Information
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CAS No. 2899202-97-0
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Molecular Weight 576.04
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Formula C28H18ClN3O5S2
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SMILES
O=C(C1=C(C(N(C1C2=C(O)C=CC=C2)C3=NN=C(SCC4=C(Cl)C=CC=C4)S3)=O)O)C5=CC6=C(C=CC=C6)O5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 240 Related Classifications
HY-163984 Related Classifications
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